Lean Mass and Functional Recovery in Men With Hip Fracture: A Short-Term Prospective Pilot Study

ABSTRACT OBJECTIVE To assess the capability of different definitions of low appendicular lean mass (aLM) to predict the short-term functional recovery in hip-fracture men. DESIGN We investigated 80 of 95 men with hip fracture admitted consecutively to a rehabilitation hospital. Body composition was assessed by dual-energy x-ray absorptiometry. Functional recovery after inpatient rehabilitation was evaluated using Barthel Index scores. RESULTS The patients with aLM above the cut-off value of 19.75kg indicated by the Foundation for the National Institutes of Health (FNIH) had significantly higher Barthel Index scores than those with aLM below the cut-off value(p=0.002). Patients' categorization according to the same threshold (aLM=19.75kg) was significantly associated with a Barthel Index score ≥85 after adjustment for age, cognitive impairment, hip-fracture type, comorbidities, and medications (odds ratio = 7.17; 95% CI 1.43-35.94; p = 0.017). Conversely, patients' categorization according to neither Baumgartner's cut-off value (7.26kg/m2) for aLM/height2 nor FNIH cut-off value(0.789) for aLM divided by body mass index (BMI) was significantly associated with the Barthel Index scores. CONCLUSIONS Categorization according to the FNIH threshold for aLM, but not to the FNIH threshold for aLM/BMI or Baumgartner's threshold for aLM/height2, was associated with the short-term recovery in activities of daily living following a hip-fracture in men. CORRESPONDING AUTHOR: Dr. Marco Di Monaco, Osteoporosis Research Center, Division of Physical Medicine and Rehabilitation, Presidio Sanitario San Camillo, Strada Santa Margherita 136, 10131, Torino, Italy. Tel. 0039 011 8199411; Fax 0039 011 8193012; Email Marco.di.monaco@alice.it,m.di-monaco@h-sancamillo.to.it DISCLOSURES: All the authors have no conflicts of interest. The study was not funded. The authors had no financial benefits for the study. The results have not been previously presented. Copyright © 2017 Wolters Kluwer Health, Inc. All rights reserved.

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