Recent years have seen extensive data on continuous recording of brain activity in the state of restful waking. This activity is particularly reflected in spatial maps of brain activity obtained using functional MRI scanning (fMRI) and termed resting state networks (RSN). RSN have stable spatial structure which is reproducible over time in healthy subjects, but can be significantly different from normal in the presence of clinical pathology. One important parameter of this type of brain activity is the functional connectivity (FC) of individual elements within the network or between RSN. This review describes results from studies of the interaction of behavioral parameters and FC in brain areas active in the state of restful waking. Data on the reproducibility of RSN parameters over time in healthy subjects are presented, along with data on changes in the FC of networks depending on individual experience.
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