Liver disease predicts mortality in patients with XHIM but can be prevented by early hematopoietic stem cell transplantation

Publication date: Available online 26 July 2017
Source:Journal of Allergy and Clinical Immunology
Author(s): Vian Azzu, Lucinda Kennard, Beatriz Morillo-Gutierrez, Mary Slatter, J.David M. Edgar, Dinakantha S. Kumararatne, William JH. Griffiths

Teaser

In the largest detailed study of liver disease in X-linked immunodeficiency with hyper-IgM, we show that liver disease is commoner than generally recognized and that early hematopoietic stem cell transplantation may prevent liver disease progression and improve survival.


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