Early childhood myoclonic epilepsy: An independent genetic generalized epilepsy with myoclonic seizures as the main seizure type

Genetic (idiopathic) generalized epilepsies (GGEs) constitute one-third of all epilepsies (ILAE, 1989; Engel and ILAE, 2001). They are genetically determined and affect otherwise normal individuals of both sexes. GGEs manifest with absences, myoclonic jerks or generalized tonic-clonic seizures (GTCS), alone or in varying combinations and severity (Panayiotopoulos, 2005). According to the age at onset, GGEs proposed by International League Against Epilepsy (ILAE) include: myoclonic epilepsy in infancy (MEI), epilepsy with myoclonic absences (MAE), epilepsy with myoclonic atonic seizures also named as Doose syndrome, childhood absence epilepsy (CAE), juvenile absence epilepsies (JAE), and juvenile myoclonic epilepsy (JME) and so on (Berg et al., 2010).

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