Τετάρτη 14 Ιουνίου 2017

Associating cellular epigenetic models with human phenotypes

Nature Reviews Genetics 18, 441 (2017). doi:10.1038/nrg.2017.32

Authors: Tuuli Lappalainen & John M. Greally

Epigenetic association studies have been carried out to test the hypothesis that environmental perturbations trigger cellular reprogramming, with downstream effects on cellular function and phenotypes. There have now been numerous studies of the potential molecular mediators of epigenetic changes by epigenome-wide association studies (EWAS). However,



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