The importance of electrophysiological assessment of myoclonus

There are very few examples in Neurology, especially in the field of Movement Disorders, where clinical assessment might subside to electrophysiological testing, but myoclonus is one of these. The challenge in the diagnosis of myoclonus is probably reflected by the fact that it can be classified in a number of ways, depending on etiology, presumed source of its generation, activity during which it occurs (i.e., rest, action, etc.) and bodily distribution [Kojovic et al., 2011]. Among all these, the classification based on the putative site of myoclonus origin, or in other words deducing "Where is the lesion?", is of extreme importance, as it will guide therapeutic decisions [Caviness, 2014].

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