Distinctive neuronal firing patterns in subterritories of the subthalamic nucleus

Subthalamic nucleus deep brain stimulation (STN-DBS) is an established treatment for advanced Parkinson's disease (PD). Several studies have demonstrated its effectiveness in improving PD-related motor symptoms (Benabid et al. 2009; Fasano et al. 2012), including younger patients and those at a less advanced disease stage (Schuepbach et al. 2013). An accurate DBS lead location, within the presumed sensorimotor domain of the STN (dorsolateral, dSTN), is crucial to obtain optimal motor benefit (Herzog et al.

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