Real-time multi-channel monitoring of burst-suppression using neural network technology during pediatric status epilepticus treatment

Status epilepticus is a condition resulting either from the failure of the mechanisms responsible for seizure termination or from the initiation of mechanisms, which lead to abnormally, prolonged seizures (Trinka et al., 2015). Convulsive SE is the most common childhood neurological emergency in developed countries with 18-20 episodes per 100,000 cases per year in children younger than 16 years old (Chin et al., 2004; 2006). Because of its significant morbidity and mortality (Logroscino et al., 2001; Claassen et al., 2002; DeLorenzo et al., 1996), SE requires prompt diagnosis and treatment.

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