INFLUENCE OF END STAGE RENAL DISEASE IN ALTERATION OF SOME TRACE ELEMENTS IN SUDANESE PATIENTS

2016-06-07T23-38-39Z
Source: International Journal of Current Research and Review
Kamal Eldin Ahmed Abdelsalam, Eshteag Mohammed Musllem.
Background: The role of trace elements in hemodialysis (HD) patients has not yet been clearly recognized. To minimize the health consequences of persistent HD, the levels of trace elements should be seriously adjusted. Methods: The study was across-sectional conducted in Khartoum state of Sudan between August 2013 and April 2015 included 150 patients with end stage renal disease treated with hemodialysis and 75 healthy volunteers as control group. Informed consent was assigned by each participant before taking the blood sample. All samples were analyzed for magnesium, zinc and copper. Results: Compared with healthy controls, in hemodialysis patients average serum levels of zinc (Zn) (663 μg/L) and copper (Cu) (797μg/L) were insignificantly different; however, magnesium (Mg) levels (38.61 mg/L) were significantly increased. According to sex of ESRD patients, serum Mg level was increased significantly in females, while insignificant changes were observed in Cu level. This study stated that Zn, Cu and Mg levels were significantly increased in elder patients more than younger ones. Zn, Cu and Mg were increased as increasing duration of dialysis, changing significantly in serum Zn and Cu. Conclusions: Our results concluded that in hemodialysis, aging, and sex have significant effects on Zn, Cu and Mg.


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