Improved multi-stage neonatal seizure detection using a heuristic classifier and a data-driven post-processor

Seizures are a common and distinctive sign of serious brain dysfunction in neonates (Volpe 2008). The majority of neonatal seizures have an acute symptomatic basis and one of the most important causes is hypoxic ischemic encephalopathy (HIE) (Hahn and Olson 2004; Cherian et al. 2011). Clinical presentation can be highly variable and manifestations of neonatal seizures can be subtle, absent or resemble normal behavior. It is known that after treating with anticonvulsants,clinical seizures will change in subclinical seizures (Connell et al.

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