The Hallmarks of Rheumatic Fever in Developing Countries (Pakistan and Afghanistan)

2016-03-30T16-28-47Z
Source: Annals of Paediatric Rheumatology
Muhammad Ishaq, Sameera Ishaq, Imran Khan, Sabeen Khan Al-Juniad.
Rheumatic fever is a multisystem disorder resulting from post streptococcal infection. It reflects a generalized vasculitic process with the following features: (1) rheumatic arthritis (significantly affecting the large joints), (2) carditis, (3) rheumatic chorea, (4) erythema marginatum, and (5) subcutaneous nodules. In this study, we observed these features singly or in variable combinations. Initially, acute rheumatic fever with carditis, in some untreated cases, progressed to chronic rheumatic heart disease, with devastating outcome.


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