Non-invasive cortical modulation of experimental pain in migraine

The migraine pathophysiology is partly unknown, but it is generally accepted that dysfunction of central nervous system (CNS) structures is involved, causing unstable CNS-excitability. This dysfunction could cause migraine attacks by increasing the susceptibility for activation and sensitization of the trigeminovascular pain pathway (Vecchia et al., 2012, Noseda et al., 2013).

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