Fitness Is Independently Associated with Central Hemodynamics in Metabolic Syndrome.

Purpose: Fit individuals with metabolic syndrome (MetS) have lower mortality risk compared to less fit counterparts, despite the presence of obesity as a component of the syndrome. To understand the importance of fitness in treating this condition, we examined the association of fitness and fatness with central hemodynamic indices that are known independent predictors of cardiovascular events (CVEs). Methods: 68 individuals with MetS participated in this cross-sectional study. Central hemodynamics were calculated from radial applanation tonometry and comprised: aortic reservoir pressure, backward pressure wave (Pb), reflection magnitude (RM), and augmentation index at 75bpm (AIx75). Cardiorespiratory fitness (CRF) and body fat percentage (BF%) were determined via indirect calorimetry during maximal exercise testing and dual energy x-ray absorptiometry, respectively. Results: CRF was inversely associated with aortic reservoir pressure (r = -0.29, p = 0.02), Pb (r = -0.42, p

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