Editorial Board

Publication date: September 2018

Source: Gene Expression Patterns, Volume 29

Author(s):

from Genetics via xlomafota13 on Inoreader https://ift.tt/2L3GD4K
via IFTTT

South Korea: in the midst of a privacy reform centered on data sharing

Abstract

With rapid developments in genomic and digital technologies, genomic data sharing has become a key issue for the achievement of precision medicine in South Korea. The legal and administrative framework for data sharing and protection in this country is currently under intense scrutiny from national and international stakeholders. Policymakers are assessing the relevance of specific restrictions in national laws and guidelines for better alignment with international approaches. This manuscript will consider key issues in international genome data sharing in South Korea, including consent, privacy, security measures, compatible adequacy and oversight, and map out an approach to genomic data sharing that recognizes the importance of patient engagement and responsible use of data in South Korea.

from Genetics via xlomafota13 on Inoreader https://ift.tt/2nNhfqw
via IFTTT

Effects of endurance training on neuromuscular fatigue in healthy active men. Part I: Strength loss and muscle fatigue

Abstract

Purpose

The adaptations induced by endurance training on the neuromuscular function remain under investigation and, for methodological reasons, unclear. This study investigates the effects of cycling training on neuromuscular fatigue and its peripheral contribution measured during and immediately after cycling exercise.

Methods

Fourteen healthy men performed a fatigue test before a 9-week cycling program (PRE) and two tests after training: at the same absolute power output as PRE (POST_ABS) and based on the post-training maximal aerobic power (POST_REL). Throughout the tests and at exhaustion (EXH), maximal voluntary contraction (MVC) and peripheral fatigue were assessed in the quadriceps muscle by electrical nerve stimulation [single twitch (Pt); high-frequency doublet (Db₁₀₀) and low-to-high-frequency ratio (Db_10:100)].

Results

Time to EXH was longer in POST_ABS than PRE (34 ± 5 vs. 27 ± 4 min, P < 0.001), and POST_REL tended to be longer than PRE (30 ± 6 min, P = 0.053). MVC and peripheral fatigue were overall less depressed in POST_ABS than PRE at isotime. At EXH, MVC and Db_10:100 were similarly reduced in all sessions (–37 to − 42% and − 30 to − 37%, respectively). Db₁₀₀ tended to be less depressed in POST_ABS than PRE (–40 ± 9 vs. − 48 ± 16%, P = 0.050) and in POST_REL than PRE (–39 ± 9%, P = 0.071). Pt decreased similarly in POST_ABS and PRE (–52 ± 16 vs. − 54 ± 16%), but POST_REL tended to be less depressed than PRE (–48 ± 14%, P = 0.075).

Conclusions

This study confirms fatigue attenuation at isotime after training. Yet lower or similar fatigue at EXH indicates that, unlike previously suggested, fatigue tolerance may not be upregulated after 9 weeks of cycling training.

from Physiology via xlomafota13 on Inoreader https://ift.tt/2nP8Q66
via IFTTT

Motivation alters implicit temporal attention through sustained and transient mechanisms: A behavioral and pupillometric study

Psychophysiology, EarlyView.


from Physiology via xlomafota13 on Inoreader https://ift.tt/2nKJKoV
via IFTTT

Gestational chronodisruption leads to persistent changes in the rat fetal and adult adrenal clock and function

The Journal of Physiology, Volume 0, Issue ja, -Not available-.


from Physiology via xlomafota13 on Inoreader https://ift.tt/2N1O0ew
via IFTTT

Passive heat therapy protects against endothelial cell hypoxia‐reoxygenation via effects of elevations in temperature and circulating factors

The Journal of Physiology, Volume 0, Issue ja, -Not available-.


from Physiology via xlomafota13 on Inoreader https://ift.tt/2MASex0
via IFTTT

Finding the metabolic stress “sweet spot”: Implications for sprint interval training‐induced muscle remodelling

The Journal of Physiology, Volume 0, Issue ja, -Not available-.


from Physiology via xlomafota13 on Inoreader https://ift.tt/2OKevWi
via IFTTT