Assessment of changes in the micro-nano environment of intervertebral disc degeneration based on Pfirrmann grade

Pfirrmann grading can be used to assess intervertebral disc degeneration (IVDD) . There is growing evidence that IVDD is not simply a structural disorder but also involves changes to the substructural characteristics of the disc. Whether Pfirrmann grade can accurately represent these micro-nano environmental changes remains unclear.

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