Accurate RNA consensus sequencing for high-fidelity detection of transcriptional mutagenesis-induced epimutations [Genetics]

Transcriptional mutagenesis (TM) due to misincorporation during RNA transcription can result in mutant RNAs, or epimutations, that generate proteins with altered properties. TM has long been hypothesized to play a role in aging, cancer, and viral and bacterial evolution. However, inadequate methodologies have limited progress in elucidating a causal association....

from Genetics via xlomafota13 on Inoreader http://ift.tt/2x1lEMj
via IFTTT