Treatment guidelines and patterns of care in oral cavity squamous cell carcinoma: Primary surgical resection vs. nonsurgical treatment

The 2017 National Comprehensive Cancer Network (NCCN) Clinical Practice Guidelines provide level 2A recommendations for surgical excision with neck dissection or for definitive radiation therapy (RT) in early-stage oral cavity cancers, as well as 2A recommendations for surgery with postoperative adjuvant therapy or multimodality clinical trials for resectable late-stage oral cavity lesions [1]. Despite this, with significant advancements in reconstructive techniques and subsequent improvements in functional outcomes, surgical resection has become the preferred treatment modality for resectable oral cavity malignancies [2,3].

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