Lower motor neurons – counting cogs in the ALS machine

Lower motor neuron (LMN) degeneration is at the core of amyotrophic lateral sclerosis (ALS), producing much of the disability through the disease course and ultimately death from denervation of the respiratory muscles. The LMN and the muscle it innervates are uniquely accessible parts of the nervous system such that they are readily amenable to functional and structural interrogation. For this reason, there have been extensive neurophysiological and pathological studies of the diseased LMN in ALS.

from Physiology via xlomafota13 on Inoreader http://ift.tt/1S3Xbvu
via IFTTT